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mGluR5 Mouse anti-Human, Mouse, Rat, Clone: S75-3, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527691

Catalog No. PIMA527691


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Description

Description

GRK1 is a member of the guanine nucleotide protein-coupled (G protein) receptor kinase subfamily of Serine/Threonine kinase family. GRK1 phosphorylates rhodopsin and initiates its deactivation. G protein mediated phosphorylation promotes the binding of arrestin, which removes the receptor from the G-protein and terminates the receptor signal chain. GRK1 is farnesylated to promote membrane association. Studies have shown that GRK1 has been shown to be inhibited by recoverin, a Calcium binding protein. Diseases associated with GRK1 protein dysfunction include Oguchi Disease-2 and Hereditary Night Blindness.
Specifications

Specifications

mGluR5
Monoclonal
1 mg/ml
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
P31424, P41594, Q3UVX5
mGluR, metabotropic glutamate receptor 5, metabotropic glutamate receptor 1, mGlu5, mGlu1, mGluR5, mGluR1, GPRC1E, GRM5, Metabotropic glutamate receptor 5 variant F, Metabotropic glutamate receptor 5 variant G, Metabotropic glutamate receptor 5 variant H, Glutamate receptor metabotropic 5
Mouse
IgG2A
100 μg
-20°C
Primary
108071, 24418, 2915
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
S75-3
Unconjugated
GRM5
Liquid
GRM5
Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b
Protein G
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Documents
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