mGluR5 Mouse anti-Human, Mouse, Rat, Clone: S75-3, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527691
DescriptionGRK1 is a member of the guanine nucleotide protein-coupled (G protein) receptor kinase subfamily of Serine/Threonine kinase family. GRK1 phosphorylates rhodopsin and initiates its deactivation. G protein mediated phosphorylation promotes the binding of arrestin, which removes the receptor from the G-protein and terminates the receptor signal chain. GRK1 is farnesylated to promote membrane association. Studies have shown that GRK1 has been shown to be inhibited by recoverin, a Calcium binding protein. Diseases associated with GRK1 protein dysfunction include Oguchi Disease-2 and Hereditary Night Blindness.
|PBS with 50% glycerol and 0.09% sodium azide; pH 7.4|
|P31424, P41594, Q3UVX5|
|mGluR, metabotropic glutamate receptor 5, metabotropic glutamate receptor 1, mGlu5, mGlu1, mGluR5, mGluR1, GPRC1E, GRM5, Metabotropic glutamate receptor 5 variant F, Metabotropic glutamate receptor 5 variant G, Metabotropic glutamate receptor 5 variant H, Glutamate receptor metabotropic 5|
|108071, 24418, 2915|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot|
|Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b|
|Human, Mouse, Rat|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok