Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

MHC Class II Rat anti-Canine, FITC, Clone: YKIX334.2, eBioscience™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

Manufacturer:  Invitrogen 11590942

Catalog No. 50-112-2149


Add to cart

Description

Description

Description: This YKIX334.2 monoclonal antibody reacts with canine major histocompatibility complex (MHC) Class II. The MHC plays a significant role in immunity by presenting self and non-self antigens to T cells. In dogs, MHC Class II is expressed on all T and B cells, macrophages, fibroblasts, and kidney interstitial cells. This monoclonal antibody has been reported to inhibit mixed lymphocyte reactions and T cell activation induced by MHC Class II antigen presentation in vitro. Also, YKIX334.2 recognition of MHC Class II is not allele-specific. Applications Reported: This YKIX334.2 antibody has been reported for use in flow cytometric analysis. Applications Tested: This YKIX334.2 antibody has been pre-titrated and tested by flow cytometric analysis of canine peripheral blood cells. This can be used at 5 µL (0.5 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser. Filtration: 0.2 µm post-manufacturing filtered.

MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long.
Specifications

Specifications

MHC Class II
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
Major histocompatibility complex class II; MHC 2; MHC Class II; MHC II; MHCCII
IgG2a, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
Canine
Flow Cytometry
YKIX334.2
FITC
Liquid
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Documents
Provide Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

For Research Use Only.