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MHC Class II Rat anti-Mouse, Alexa Fluor™ 750, Clone: M5/114, Novus Biologicals™

Rat Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP221789AF750

Catalog No. NP221789A70


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Description

Description

MHC Class II Monoclonal antibody specifically detects MHC Class II in Mouse samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen).
Specifications

Specifications

MHC Class II
M5/114
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Conjugated, Purified
HLA-DMA
Activated C57BL/6 mouse spleen cells
Protein G purified
Adaptive Immunity, Asthma, B Cell Development and Differentiation Markers, Cell Biology, Diabetes Research, Immune System Diseases, Immunology, Major Histocompatibility Complexes, Transcription Factors and Regulators
Primary
3108.0
Mouse
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Alexa Fluor™ 750
50 mM sodium borate with 0.05% sodium azide
class II histocompatibility antigen, M alpha chain, D6S222E, DMA, HLA class II histocompatibility antigen, DM alpha chain, major histocompatibility complex, class II, DM alpha, MHC class II antigen DMA, Really interesting new gene 6 protein, RING6HLADM
Rat
IgG2b
0.1 mL
Store at 4°C in the dark.
Monoclonal
The rat monoclonal antibody M5/114 reacts with murine MHC class II glycoproteins. It recognizes a shared determinant on I-Ab, I-Ad, I-Aq, and I-Ed, I-Ek alloantigens, but it does not react with I-Af, I-Ak, I-As. This antibody can inhibit I-A-restricted T cell responses of the H-2b, H-2d, H-2q, H-2u but not H-2f, H-2k, H-2s haplotypes.
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