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MHC class II (I-A/I-E) Rat anti-Mouse, Janelia Fluor 549, Clone: M5/114.15.2, Novus Biologicals™

Rat Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP143312JF549

Catalog No. NBP43312549


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Description

Description

MHC class II (I-A/I-E) Monoclonal antibody specifically detects MHC class II (I-A/I-E) in Mouse samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen).
Specifications

Specifications

MHC class II (I-A/I-E)
M5/114.15.2
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Purified
H2-Ea-ps
The immunogen for this antibody was MHC Class II.
Protein A or G purified
Adaptive Immunity, Asthma, B Cell Development and Differentiation Markers, Cell Biology, Diabetes Research, Immune System Diseases, Immunology, Major Histocompatibility Complexes, Transcription Factors and Regulators
Primary
100504404
Mouse
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Janelia Fluor 549
50mM Sodium Borate with 0.05% Sodium Azide
class II histocompatibility antigen, M alpha chain, D6S222E, DMA, HLA class II histocompatibility antigen, DM alpha chain, major histocompatibility complex, class II, DM alpha, MHC class II antigen DMA, Really interesting new gene 6 protein, RING6HLADM
Rat
IgG2b Kappa
0.1mL
Store at 4°C in the dark.
Monoclonal
The monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2 b, H-2 d, H-2 q, H-2 p, H-2 r and H-2 u but not from mice carrying the H-2 s or H-2 f haplotypes. The M5/114 mAb is reported to inhibit I-A-restricted T cell responses of the H-2 b, H-2 d, H-2 q, H-2 u but not H-2 f, H-2 k, or H-2 s haplotypes.
SDS
Documents
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