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Tocris Bioscience MI 2 dihydrochloride
Menin-MLL interaction inhibitor
Manufacturer: Tocris Bioscience 4707/50
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Description
Menin-MLL interaction inhibitor; binds menin (IC50 = 446 nM). Selectively inhibits proliferation and induces apoptosis of leukemia cells harboring MLL fusion proteins. Also blocks transformation and induces hematopoietic differentiation of MLL-AF9 transformed bone marrow cells.Specifications
4-[4-(4,5-Dihydro-5,5-dimethyl-2-thiazolyl)-1-piperazinyl]-6-propylthieno[2,3-d]pyrimidine dihydrochloride | |
448.48 | |
Target: Methyltransferase Inhibitors |
C18H25N5S2.2HCl | |
50mg | |
>98% |
Safety and Handling
Recommended Storage : Store at −20°C
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