Tocris Bioscience MI 2 dihydrochloride
Menin-MLL interaction inhibitor
Manufacturer: Tocris Bioscience 4707/50
DescriptionMenin-MLL interaction inhibitor; binds menin (IC50 = 446 nM). Selectively inhibits proliferation and induces apoptosis of leukemia cells harboring MLL fusion proteins. Also blocks transformation and induces hematopoietic differentiation of MLL-AF9 transformed bone marrow cells.
|Target: Methyltransferase Inhibitors|
Safety and Handling
Recommended Storage : Store at −20°C
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