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Tocris Bioscience™ MI 2 dihydrochloride

Menin-MLL interaction inhibitor

Manufacturer:  Tocris Bioscience™ 4707/50

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Catalog No. 47-075-0


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Description

Description

Menin-MLL interaction inhibitor; binds menin (IC50 = 446 nM). Selectively inhibits proliferation and induces apoptosis of leukemia cells harboring MLL fusion proteins. Also blocks transformation and induces hematopoietic differentiation of MLL-AF9 transformed bone marrow cells.
Specifications

Specifications

4-[4-(4,5-Dihydro-5,5-dimethyl-2-thiazolyl)-1-piperazinyl]-6-propylthieno[2,3-d]pyrimidine dihydrochloride
C18H25N5S2.2HCl
50mg
>98%
448.48
Target: Methyltransferase Inhibitors
Safety and Handling

Safety and Handling

Recommended Storage : Store at −20°C

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