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Mili / PiwiL2 Mouse anti-Mouse, Active Motif™ Non-distribution product as customer accommodation.

Mouse Recombinant Monoclonal Antibody

$98.40 - $465.85

Specifications

Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Antigen Mili / PiwiL2
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-3776 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
91254
10 μg
Each for $98.40
Add to cart
 
50-199-3775 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
91253
100 μg
Each for $465.85
Add to cart
 
Description

Description

The piwi gene of Drosophila belongs to a novel class of evolutionarily conserved genes (the piwi or Argonaute family). The Piwi family is required for germ and stem cell development in invertebrates, and two Piwi members, MIWI and MILI (Miwi like, Piwil2, Piwi-like protein 2), are essential for spermatogenesis in mouse. MIWI and MILI partner with Piwi-interacting RNAs (piRNAs) which are 26-31 nucleotides in length clearly distinct from the 21-23 nucleotides of microRNAs (miRNAs) or short interfering RNAs (siRNAs). A search for murine small RNAs that might program Piwi proteins for transposon suppression revealed developmentally regulated piRNA loci, some of which resemble transposon master control loci of Drosophila. MILI might be programmed by distinct piRNA populations at different stages of germ cell development, suggesting MILI plays an important role in meiotic prophase progression.
Specifications

Specifications

Monoclonal
Primary
Mili / PiwiL2
Unconjugated
SDS
Product Certifications
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