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MIM1, Tocris Bioscience™

Catalog Number 476210
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
509102-00-5
C17H21N3O3S
347.43
UXHKLJMFCANPNV-UHFFFAOYSA-N
mim1, 4-2-cyclohexylimino-4-methyl-2,3-dihydro-1,3-thiazol-3-yl imino methyl benzene-1,2,3-triol, 4-e-2z-2-cyclohexylimino-4-methyl-1,3-thiazol-3 2h-yl imino methyl benzene-1,2,3-triol, 4-n-2-cyclohexylimino-4-methyl-2,3-dihydro-1,3-thiazol-3-yl carboximidoyl benzene-1,2,3-triol
16241412
This item is not returnable. View return policy
509102-00-5
C17H21N3O3S
347.43
UXHKLJMFCANPNV-UHFFFAOYSA-N
mim1, 4-2-cyclohexylimino-4-methyl-2,3-dihydro-1,3-thiazol-3-yl imino methyl benzene-1,2,3-triol, 4-e-2z-2-cyclohexylimino-4-methyl-1,3-thiazol-3 2h-yl imino methyl benzene-1,2,3-triol, 4-n-2-cyclohexylimino-4-methyl-2,3-dihydro-1,3-thiazol-3-yl carboximidoyl benzene-1,2,3-triol
16241412

Mcl-1 inhibitor; proapoptotic

Inhibitor of Mcl-1. Inhibits Mcl-1 indirectly by induction of the proapoptotic Mcl-1 ligand NOXA via the unfolded protein response (UPR) pathway. Sensitizes leukemia cells to the Bcl-2 inhibitor venetoclax (ABT-199). Induces caspase-3/7 activation and cell death in Mcl-1-dependent leukemia cells. Also blocks Mcl-1-mediated suppression of tBID-induced Bax activation in vitro.
Quantity 10 mg
Formula Weight 347.43
Percent Purity >98%
Chemical Name or Material MIM1
Recommended Storage Store at +4°C
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