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Tocris Bioscience™ Mirabegron

Potent and selective β3 agonist

$83.00 - $324.50

Specifications

CAS 223673-61-8
Chemical Name or Material 2-Amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide
Molecular Formula C21H24N4O2S
Purity 98%
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
70-702-5
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Tocris Bioscience™
7070/25
25 mg
Each for $324.50
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70-705
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Tocris Bioscience™
7070/5
5 mg
Each for $83.00
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Description

Description

  • Potent and selective β3-adrenoceptor agonist (EC50 = 22.4 nM).
  • Displays >440-fold selectivity for β3 over β1 and β2 adrenoceptors.
  • Increases cAMP concentration in CHO cells expressing human β3-adrenoceptor.
  • Displays relaxant effect in ex vivo rat bladder muscle preparation precontracted with carbachol
  • Decreases frequency of bladder contraction in rats.
  • Also promotes browning of white adipose tissue, reduces body weight, and improves glucose tolerance and insulin sensitivity in mice fed a high fat diet.
Specifications

Specifications

223673-61-8
2-Amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-thiazoleacetamide
C21H24N4O2S
98%
SDS
Product Certifications
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