Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

MKL2 Mouse anti-Human, Clone: CL1546, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524628

Catalog No. PIMA524628


Add to cart

Description

Description

Immunogen sequence: QRPGPMELVE KNILPVDSSV KEAIIGVGKE DYPHTQGDFS FDEDSSDALS PDQPASQESQ GSAASPSEPK VSESPSPVTT NTPAQFASVS PTVPEFLKTP PTADQPPPRP AAPVLPTNTV SSAKPGPALV KQSHPKNP Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 54%. Binds to an epitope located within the peptide sequence FASVSPTVPEFLKTP as determined by overlapping synthetic peptides.

Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF regulates the transient response of several muscle genes in response to growth factors and recruits accessory myogenic factors to activate these muscle genes. SRF is required for the formation of vertebrate mesoderm leading to the origin of the cardiovascular system. Myocardin, in association with SRF in cardiac muscle cells, activates cardiac muscle promoters. Myocardin-related transcription factors A and B (MRTF-A and MRTF-B) interact with SRF and act as stimulators for its transcriptional activity. MRTF-B is crucial for skeletal myogenic differentiation.
Specifications

Specifications

MKL2
Monoclonal
1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q9ULH7
MKL/myocardin-like protein 2, Megakaryoblastic leukemia 2, Myocardin-related transcription factor B, MRTF-B, MKL2, KIAA1243, MRTFB
Mouse
IgG1
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
57496
Western Blot
CL1546
Unconjugated
MKL2
Liquid
MKL2
Recombit protein corresponding to Human MKL2
Protein A
RUO
Antibody
Monoclonal
Human
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

Research Use Only