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MKT 077, Tocris Bioscience™

Catalog Number 462150
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50mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Binds mot-2; selectively cytotoxic in cancer cells

Occupies mortalin-2 (mot-2), a member of the Hsp70 family, at its p53 binding site and enables p53 translocation to the nucleus. Selectively cytotoxic; causes growth arrest of cancer cells in culture. Also inhibits telomerase activity and cross-links F-actin.
CAS 147366-41-4
Molecular Formula C21H22ClN3OS2
Quantity 50 mg
MDL Number MFCD00953420
Synonym 1-Ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]-pyridinium chloride
InChI Key VSKYOTRJSLYFHX-UXJRWBAGSA-M
SMILES [Cl-].CCN1C(S\C(C1=O)=C1\SC2=CC=CC=C2N1C)=CC1=CC=CC=[N+]1CC
IUPAC Name 1-ethyl-2-({3-ethyl-5-[(2E)-3-methyl-2,3-dihydro-1,3-benzothiazol-2-ylidene]-4-oxo-1,3-thiazolidin-2-ylidene}methyl)pyridin-1-ium chloride
Molecular Weight (g/mol) 432.00
PubChem CID 124080978
Formula Weight 432
Percent Purity >98%
Chemical Name or Material MKT 077
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Safety and Handling

Recommended Storage Store at +4°C
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