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  5. Tocris Bioscience™ ML 162

Tocris Bioscience™ ML 162
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Inhibits glutathione peroxidase (GPX4); induces ferroptosis

$186.40 - $758.50

Specifications

Chemical Name or Material 2-[(Chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide
CAS 1035072-16-2
Target Glutathione Peroxidase 4/GPX4
Molecular Formula C23H22Cl2N2O3S
Purity 0.98
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
78-211-0
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Tocris Bioscience™
7821/10 		10 mg
Each for $186.40
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78-215-0
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Tocris Bioscience™
7821/50 		50 mg
Each for $758.50
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Description

Description

ML 162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor. It induces ferroptosis in vivo. It is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50 = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively).
Specifications

Specifications

2-[(Chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide
Glutathione Peroxidase 4/GPX4
0.98
1035072-16-2
C23H22Cl2N2O3S
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Safety and Handling

Recommended Storage : Store at -20°C

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