DescriptionRORγt inverse agonist (IC50 = 460 nM). Suppresses Th17 cell differentiation and IL17A expression in vitro. Does not suppress transcription of RORα. Minimal activity displayed on ERα, LXRα and thyroid hormone receptors (IC50 values >4.4 μM).
|Agonist against RORγt|
|Soluble to 100mM in DMSO|
|Store at 4°C|
For Laboratory Research Use Only
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