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ML 228, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
50mg
This item is not returnable. View return policy
1357171-62-0
C27H21N5
415.5
QNRODODTMXCRKU-UHFFFAOYSA-N
n-1,1'-biphenyl-4-ylmethyl-6-phenyl-3-pyridin-2-yl-1,2,4-triazin-5-amine,ml228 probe,6-phenyl-n-4-phenylphenyl methyl-3-2-pyridinyl-1,2,4-triazin-5-amine,n-1,1'biphenyl-4-ylmethyl-6-phenyl-3-2-pyridinyl-1,2,4-triazin-5-amine,n-biphenyl-4-ylmethyl-6-phenyl-3-pyridin-2-yl-1,2,4-triazin-5-amine
46742353
6-phenyl-N-[(4-phenylphenyl)methyl]-3-pyridin-2-yl-1,2,4-triazin-5-amine
C1=CC=C(C=C1)C2=CC=C(C=C2)CNC3=C(N=NC(=N3)C4=CC=CC=N4)C5=CC=CC=C5
This item is not returnable. View return policy
1357171-62-0
C27H21N5
415.5
QNRODODTMXCRKU-UHFFFAOYSA-N
n-1,1'-biphenyl-4-ylmethyl-6-phenyl-3-pyridin-2-yl-1,2,4-triazin-5-amine,ml228 probe,6-phenyl-n-4-phenylphenyl methyl-3-2-pyridinyl-1,2,4-triazin-5-amine,n-1,1'biphenyl-4-ylmethyl-6-phenyl-3-2-pyridinyl-1,2,4-triazin-5-amine,n-biphenyl-4-ylmethyl-6-phenyl-3-pyridin-2-yl-1,2,4-triazin-5-amine
46742353
6-phenyl-N-[(4-phenylphenyl)methyl]-3-pyridin-2-yl-1,2,4-triazin-5-amine
C1=CC=C(C=C1)C2=CC=C(C=C2)CNC3=C(N=NC(=N3)C4=CC=CC=N4)C5=CC=CC=C5

HIF pathway activator

HIF pathway activator (EC50 values are 1.23 and 1.4 μM for HRE gene reporter assay and HIF-1α nuclear translocation assay respectively); acts via chelation of iron, independently of PHD. Also exhibits > 80% inhibition of the human A3 receptor, dopamine transporter, μ receptor, hERG and 5-HT2B receptor, and rat sodium channel site 2, at a concentration of 10 μM.

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Quantity 50mg
Formula Weight 415.49
Percent Purity >98%
Chemical Name or Material ML 228

Recommended Storage : Store at -20°C