Tocris ML 277
Selective Kv7.1 (KCNQ1) potassium channel activator; augments IKs current
Manufacturer: Tocris 4777/50
DescriptionSelective Kv7.1 (KCNQ1) potassium channel activator (EC50 = 260nM). Exhibits >100-fold selectivity versus KCNQ2, KCNQ4 and hERG potassium channels. Augments IKs current of cultured human cardiomyocytes and shortens action potential duration.
- Chemical Name: (2R)-N-[4-(4-Methoxyphenyl)-2-thiazolyl]-1-[(4-methylphenyl)sulfonyl]-2-piperidinecarboxamide
- Formula: C23H25N3O4S2
- CAS Number: 1401242-74-7
- Solubility: Soluble to 100mM in DMSO
- Purity: >98
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok