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Tocris™ ML 337

Selective negative allosteric modulator of mGlu3

Manufacturer:  Tocris™ 4982/50

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Catalog No. 49-825-0R

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For Research Use Only



Selective negative allosteric modulator of mGlu3 (IC50 = 593nM). Displays no activity at mGlu1, mGlu2 or mGlu4-8 at concentrations up to 30µM. Brain penetrant.
  • Chemical Name: [2-Fluoro-4-[2-(4-methoxyphenyl)ethynyl]phenyl][(3R)-3-hydroxy-1-piperidinyl]methanone
  • Formula: C21H20FNO3
  • CAS Number: 1443118-44-2
  • Solubility: Soluble to 100mM in DMSO and to 20mM in ethanol
  • Purity: >98
Description & Specifications


ML 337
ML 337
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