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MLF1 Mouse anti-Human, Clone: OTI3E7, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA504827

Catalog No. 50-167-5433


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Description

Description

MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Specifications

Specifications

MLF1
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P58340
myeloid leukemia factor 1
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
4291
Western Blot
OTI3E7
Unconjugated
MLF1
Liquid
MLF1
Full length human recombit protein of human MLF1 produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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