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MLF1 Monoclonal Antibody (OTI3F11), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Supplier: OriGene TA504767
Description
MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.Specifications
MLF1 | |
Monoclonal | |
1 mg/mL | |
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
P58340 | |
MLF1 | |
Full length human recombit protein of human MLF1 produced in E.coli. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG2b |
Immunohistochemistry (Paraffin), Western Blot | |
OTI3F11 | |
Unconjugated | |
MLF1 | |
myeloid leukemia factor 1 | |
Mouse | |
Affinity Chromatography | |
RUO | |
4291 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
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