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MLF1 Mouse anti-Human, Clone: OTI3A3, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525975

Catalog No. PIMA525975


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Description

Description

MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Specifications

Specifications

MLF1
Monoclonal
0.93 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P58340
Myeloid leukemia factor 1; Myelodysplasia-myeloid leukemia factor 1; MLF-1
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
4291
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI3A3
Unconjugated
MLF1
Liquid
MLF1
Full length human recombit protein of MLF1 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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