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KMT2D Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549581

Catalog No. PA549581


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Description

Description

KMT2D is a histone methyltransferase that methylates Lys-4 of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. KMT2D acts as a coactivator for estrogen receptors by being recruited by ESR1 and activating transcription. KMT2D is involved in chromatin organization, chormatin silencig, oocyte growth, oogenesis, and a positive regulation of cell proliferation. Mutations in the KMT2D gene cause Kabuki syndrome (KABUK1) which results in congential mental retardation syndrome.
Specifications

Specifications

KMT2D
Polyclonal
Unconjugated
KMT2D
Liquid
KMT2D
KLH conjugated synthetic peptide between 4980-5009 amino acids from the C-terminal region of human MLL2.
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Human
Western Blot
0.5 mg/mL
PBS with 0.09% sodium azide
O14686
Histone-lysine N-methyltransferase 2D, Lysine N-methyltransferase 2D, ALL1-related protein, Myeloid/lymphoid or mixed-lineage leukemia protein 2, KMT2D, ALR, MLL2, MLL4
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
8085
Documents
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