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MME Mouse anti-Human, Clone: OTI3D11, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA504507

Catalog No. 50-167-5180


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Description

Description

CD10 (Common Acute Lymphocytic Leukemia Antigen ,CALLA), is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt ft.s, and follicular germinal center lymphomas, immature B cells with in adult bone marrow and on cells from patients with chronic myelocytic leukemia (CML). CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells. CD10 is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. Further, CD10 is a 100 kDa type II transmembrane glycoprotein that exists in a single copy of greater than 45 kb. The 5 ft. untranslated region of the CD10 gene is alternatively spliced, resulting in four separate mRNA transcripts and the coding region is not affected by alternative splicing. Diseases associated with CD10 dysfunction include spinocerebellar ataxia 43 and Charcot-Marie tooth Disease.
Specifications

Specifications

MME
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P08473
CALLA, CD10, CMT2T, NEP, SCA43, SFE
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
4311
Immunohistochemistry (Paraffin), Western Blot
OTI3D11
Unconjugated
MME
Liquid
MME
Full length human recombit protein of human MME produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
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