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Thermo Scientific™ Lab Vision™ MMP-1 (Collagenase-1) Ab-6, Rabbit Polyclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with the Thermo Scientific™ MMP-1 (Collagenase-1) Ab-6, Rabbit Polyclonal Antibody.

Specifications

Antigen MMP-1 (Collagenase-1) Ab-6
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
Host Species Rabbit
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Products 1
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
RB1536R1
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Thermo Scientific™
RB1536R1
Ready-to-use for IHC (UVLP) 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with the Thermo Scientific™ MMP-1 (Collagenase-1) Ab-6, Rabbit Polyclonal Antibody.

Matrix metalloproteinases (MMP) are proteolytic enzymes capable of degrading connective tissue components. Imbalanced secretion of certain MMP or disturbances in the differential control of MMP by tissue inhibitor of MMPs (TIMPs) are implicated in the invasive potential of malignant tumors. Interstitial collagenase (MMP-1), 72kDa gelatinase A/type IV collagenase (MMP-2), and 92kDa gelatinase B/type IV collagenase (MMP-9) dissolve extracellular matrix (ECM) and may initiate and promote angiogenesis.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human. Does not react with cow. Others not known.

Epitope: Middle region of MMP-1

Immunogen: A synthetic peptide from the middle region of the human MMP-1

Molecular Weight: 52kDa (unglycosylated) and 57kDa (glycosylated) species of proform of MMP-1 plus 42kDa (unglycosylated) and 47kDa (glycosylated) active form of MMP-1

Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells; Placenta; Bladder, breast, ovarian, colon CA

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

MMP-1 (Collagenase-1) Ab-6
Polyclonal
Rabbit
Proteases And Inhibitors
A synthetic peptide from the middle region of the human MMP-1
Immunohistochemistry (Paraffin)
Unconjugated
RUO
Primary
IgG
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