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Thermo Scientific™ Lab Vision™ MMP-10 (Stromelysin-2) Ab-2, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with the Thermo Scientific™ MMP-10 (Stromelysin-2) Ab-2, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ MS822P0

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Catalog No. MS822P0


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Description

Description

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with the Thermo Scientific™ MMP-10 (Stromelysin-2) Ab-2, Mouse Monoclonal Antibody.

Matrix metalloproteinases (MMP) are proteolytic enzymes capable of degrading extracellular matrix. Stromelysin, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen. The two forms of stromelysin (SL), types 1 (MMP-3) and 2 (MMP-10), share 82% sequence homology, but exhibit differences in cellular synthesis and inducibility by cytokines and growth factors in vitro.

Host Species: Mouse

Clone: IVC5

Isotype: IgG2b

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Human recombinant MMP-10 (stromelysin-2 protein)

Molecular Weight: ~57kDa (proform) and ~44kDa (active form)

Positive Control: Conditioned, serum-free medium from (TPA-treated) human large cell lymphoma U937 cells; Placenta; Bladder, breast and ovarian CAs

Cellular Localization: Cytoplasmic

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

MMP-10 (Stromelysin-2) Ab-2
Monoclonal
200μg/mL
Concentrated
Human recombinant MMP-10 (stromelysin-2 protein)
100μL
Proteases And Inhibitors
Primary
Human
Immunoprecipitation, Western Blot
IVC5
Unconjugated
Murine
IgG2b
RUO
Primary
Monoclonal
SDS
Documents
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