MMP-10 (Stromelysin-2) Ab-2 Mouse Monoclonal Antibody, Epredia™

Epredia™ MMP-10 (Stromelysin-2) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.

Supplier:  Epredia MS822P1ABX

Catalog No. MS822P1ABX

Description

Matrix metalloproteinases (MMP) are proteolytic enzymes capable of degrading extracellular matrix. Stromelysin, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen. The two forms of stromelysin (SL), types 1 (MMP-3) and 2 (MMP-10), share 82% sequence homology, but exhibit differences in cellular synthesis and inducibility by cytokines and growth factors in vitro.

Host Species: Mouse

Clone: IVC5

Isotype: IgG2b

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Human recombinant MMP-10 (stromelysin-2 protein)

Molecular Weight: ∽57kDa (proform) and ∽44kDa (active form)

Positive Control: Conditioned, serum-free medium from (TPA-treated) human large cell lymphoma U937 cells; Placenta; Bladder, breast and ovarian CAs

Cellular Localization: Cytoplasmic

Recommended for:

• Western Blotting
• Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: MMP-10 (Stromelysin-2) Ab-2
• Classification: Monoclonal
• Concentration: 1mg/mL
• Host Species: Mouse
• Quantity: 100 μL
• Research Discipline: Proteases And Inhibitors
• Target Species: Human
• Isotype: IgG2b

• Applications: Immunoprecipitation, Western Blot
• Clone: IVC5
• Conjugate: Unconjugated
• Immunogen: Human recombinant MMP-10 (stromelysin-2 protein)
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated