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MMP-2 (72kDa Collagenase IV) Ab-2 Mouse Monoclonal Antibody, Epredia™
Epredia™ MMP-2 (72kDa Collagenase IV) Ab-2, Mouse Monoclonal Antibody provides accurate, reproducible results.
Supplier: Epredia MS804P1
Description
MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPs and TIMPs play a significant role in regulating angiogenesis. MMP-2; also known as 72kDa collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids.Host Species: Mouse
Clone: VB3
Isotype: IgG1/κ
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Human native 72kDa MMP-2
Molecular Weight: 72kDa (proform) and ∽66kDa (active form)
Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells
Cellular Localization: Cytoplasmic
Recommended for:
- Immunohistochemistry (Not Suitable)
- Western Blotting
- Immunofluorescence
- Immunoprecipitation (Native verified)
Note:
USA: RUO; Int'l: RUO
Specifications
MMP-2 (72kDa Collagenase IV) Ab-2 | |
Monoclonal | |
200μg/mL | |
Mouse | |
500 μL | |
Proteases And Inhibitors | |
Human | |
IgG2a κ |
Immunofluorescence, Immunoprecipitation, Western Blot | |
VB3 | |
Unconjugated | |
Human native 72kDa MMP-2 | |
RUO | |
Primary | |
Concentrated |
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