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MMP-2 (72kDa Collagenase IV) Ab-4 Mouse Monoclonal Antibody, Epredia™
Epredia™ MMP-2 (72kDa Collagenase IV) Ab-4, Mouse Monoclonal Antibody provides accurate, reproducible results.
Supplier: Epredia MS806PABX
Description
MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPs and TIMPs play a significant role in regulating angiogenesis. MMP-2; also known as 72kDa collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids.Host Species: Mouse
Clone: A-Gel VC2
Isotype: IgG1
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Human APMA-activated native 72kDa MMP-2
Molecular Weight: 72kDa (proform) and ∽66kDa (active form)
Positive Control: Placenta; Bladder, breast and ovarian CAs
Cellular Localization: Cytoplasmic
Recommended for:
- Immunohistochemistry (not qualified)
Note:
USA: RUO; Int'l: RUO
Specifications
MMP-2 (72kDa Collagenase IV) Ab-4 | |
A-Gel VC2 | |
Unconjugated | |
Human APMA-activated native 72kDa MMP-2 | |
RUO | |
Primary | |
Concentrated |
Monoclonal | |
1mg/mL | |
Mouse | |
200 μL | |
Proteases And Inhibitors | |
Human | |
IgG1 |
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