MMP1 Monoclonal Antibody (3B6), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA112891

Catalog No. 01-674-092

Description

A suggested positive control for this product is colon, esophageal or gastric tissues.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: MMP1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.08% sodium azide
• Gene Accession No.: P03956
• Gene Symbols: MMP1
• Immunogen: Synthetic peptide derived from the C-terminus of the human MMP1.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 3B6
• Conjugate: Unconjugated
• Gene: MMP1
• Gene Alias: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase; CLG; CLGN; Collagenase; collagenase-like A; fibroblast collagenase; Interstitial collagenase; interstitial collagenase A; matrix metallo protease; matrix metallopeptidase 1; matrix metallopeptidase 1 (interstitial collagenase); matrix metallopeptidase 1a; matrix metallopeptidase 1a (interstitial collagenase); matrix metalloprotease 1; matrix metalloproteinase 1; matrix metalloproteinase 1a (interstitial collagenase); Matrix metalloproteinase1; Matrix metalloproteinase-1; Matrix metalloproteinase-1a; McolA; Mcol-A; MMP; MMP1; MMP-1; Mmp1a; MMP-1a; MMPs
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 4312
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid