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MMP11 Mouse anti-Human, Clone: SL3.05, Abnova™

Mouse monoclonal antibody raised against human MMP11

Manufacturer:  Abnova Corporation MAB12543

Catalog No. 89-934-561


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Description

Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq]

Specifications

Specifications

MMP11
SL3.05
Mouse monoclonal antibody raised against human MMP11
In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).
SL-3/ST3/STMY3
Mouse
IgG1, kappa
50 uL
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Monoclonal
Human
Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Unconjugated
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200) Immunoprecipitation Western Blot The optimal working dilution should be determined by the end user.
Liquid
MMP11
Recombinant protein corresponding to human MMP11.
Protein G purification
RUO
Primary
4320
SDS
Documents
Product Certifications
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