MMP11 Mouse anti-Human, Clone: SL3.05, Abnova™
Mouse monoclonal antibody raised against human MMP11
Manufacturer: Abnova Corporation MAB12543
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq]
|Mouse monoclonal antibody raised against human MMP11|
|In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot|
|Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200) Immunoprecipitation Western Blot The optimal working dilution should be determined by the end user.|
|Recombinant protein corresponding to human MMP11.|
|Protein G purification|
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