MMP13 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA595486

Catalog No. PIPA595486

Description

Reconstitution information: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

MMP13 (collagenase 3) plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC, and ACAN. MMP13 cleaves triple helical collagens, including type I, II, and III collagen-but has the highest activity with soluble type II collagen. It can degrade collagen type IV, XIV, and X. MMP13 plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization, and ossification. It is required for normal embryonic bone development and ossification. Mutations affecting the gene can lead to spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.

Specifications

• Antigen: MMP13
• Classification: Polyclonal
• Formulation: 0.2mg sodium phosphate with 0.9MG NaCl, 0.9MG NaCl, 4MG trehalose, 4MG trehalose and 0.05MG sodium azide, 0.05MG sodium azide
• Gene Accession No.: P23097, P33435, P45452
• Gene Symbols: Mmp13
• Immunogen: E.coli-derived rat MMP13 recombit protein (Position: Y99-H335).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Gene: MMP13
• Gene Alias: Collagenase 3; Matrix metalloproteinase-13; MMP-13; UMRCASE; Mmp13
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171052, 17386, 4322
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized