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MMP24 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA551333

Catalog No. PA551333


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Description

Description

The antibody detects endogenous levels of total MMP24 protein.

All cells within tissues are surrounded by an extracellular matrix (ECM) giving the tissues shape and structure. The ECM is constantly being remodeled and constant communication is maintained between cells through this matrix. Secreted proteins, termed matrix metalloproteinases (MMPs), are involved in the modulation of cell-matrix interactions. MMPs are Zn(2+)-binding endopeptidases that degrade various components of the ECM. MMPs are enzymes implicated in normal and pathologic tissue remodeling processes, wound healing, angiogenesis, and tumor invasion. These enzymes are very potent when active, and are associated with extracellular space inhibitors called TIMPs (tissue inhibitors of matrix metalloproteinases). TIMPs have been shown to block tumor cell invasion suggesting that they act as metastasis suppressor genes.
Specifications

Specifications

MMP24
Polyclonal
Unconjugated
MMP24
Liquid
MMP24
Synthetic peptide of human MMP24
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
1.3 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Q9Y5R2, Q9R0S2, Q99PW6
RP4-614O4.10, MMP25, MT-MMP5, MT5-MMP
Rabbit
IgG
100 μL
-20°C
Primary
10893, 17391, 83513
Documents
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