MMP3 Mouse anti-Human, Clone: OTI2D9, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF806873

Catalog No. 50-166-8025

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted in its pro-protein form, and is activated by extracellular proteinase cleavage. MMP3 is capable of binding to zinc and calcium ions, and has metallo-endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin. It is involved in normal cellular processes such as wound repair and tissue remodeling. Mutations in the gene can result in coronary heart disease 6.

Specifications

• Antigen: MMP3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: MMP3
• Gene Alias: CHDS6, MMP-3, SL-1, STMY, STMY1, STR1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4314
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2D9
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P08254
• Gene Symbols: MMP3
• Immunogen: Human recombit protein fragment corresponding to amino acids 246-477 of human MMP3 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1