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MMPIP hydrochloride, Tocris Bioscience™

Catalog Number 296310
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Quantity:
1 mg
10 mg
50 mg
This item is not returnable. View return policy
1215566-78-1
C19H15N3O3
333.347
PDWYBOZNEVALOV-UHFFFAOYSA-N
mmpip, mmpip hydrochloride, 6-4-methoxyphenyl-5-methyl-3-pyridin-4-yl isoxazolo 4,5-c pyridin-4 5h-one, 6-4-methoxyphenyl-5-methyl-3-pyridin-4-yl-1,2 oxazolo 4,5-c pyridin-4-one, d08uow, mmpip hplc, 6-4-methoxyphenyl-5-methyl-3-4-pyridinyl-isoxazolo 4,5-c pyridin-4 5h-one, 6-4-methoxyphenyl-5-methyl-3-4-pyridyl isoxazolo 4,5-c pyridine-4 5h-one, 6-4-methoxyphenyl-5-methyl-3-pyridin-4-yl-4h,5h-1,2 oxazolo 4,5-c pyridin-4-one
9945530
6-(4-methoxyphenyl)-5-methyl-3-pyridin-4-yl-[1,2]oxazolo[4,5-c]pyridin-4-one
CN1C(=CC2=C(C1=O)C(=NO2)C3=CC=NC=C3)C4=CC=C(C=C4)OC
This item is not returnable. View return policy
1215566-78-1
C19H15N3O3
333.347
PDWYBOZNEVALOV-UHFFFAOYSA-N
mmpip, mmpip hydrochloride, 6-4-methoxyphenyl-5-methyl-3-pyridin-4-yl isoxazolo 4,5-c pyridin-4 5h-one, 6-4-methoxyphenyl-5-methyl-3-pyridin-4-yl-1,2 oxazolo 4,5-c pyridin-4-one, d08uow, mmpip hplc, 6-4-methoxyphenyl-5-methyl-3-4-pyridinyl-isoxazolo 4,5-c pyridin-4 5h-one, 6-4-methoxyphenyl-5-methyl-3-4-pyridyl isoxazolo 4,5-c pyridine-4 5h-one, 6-4-methoxyphenyl-5-methyl-3-pyridin-4-yl-4h,5h-1,2 oxazolo 4,5-c pyridin-4-one
9945530
6-(4-methoxyphenyl)-5-methyl-3-pyridin-4-yl-[1,2]oxazolo[4,5-c]pyridin-4-one
CN1C(=CC2=C(C1=O)C(=NO2)C3=CC=NC=C3)C4=CC=C(C=C4)OC

Potent and selective negative allosteric modulator of mGlu7 receptors

Potent allosteric mGlu7-selective receptor antagonist. Inhibits agonist-induced intracellular calcium mobilization and cAMP accumulation (IC50 values are 26 and 610 nM). Displays intrinsic activity; increases forskolin-induced cAMP accumulation in the absence of an agonist (IC50 = 15 nM), indicating inverse agonist activity.
Quantity 10 mg
Formula Weight 369.8
Percent Purity >98%
Chemical Name or Material MMPIP hydrochloride
Recommended Storage Desiccate at Room Temperature
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