Tocris MN 64
Potent and selective tankyrase inhibitor
Manufacturer: Tocris 5084/10
DescriptionPotent and selective tankyrase (TNKS) inhibitor (IC50 values are 6 and 72nM for TNKS1 and TNKS2 respectively). Has no significant effect on PARP-1 or PARP-2 (IC50 >19µM). Inhibits WNT/β-catenin signaling-dependent Super-TopFlash (STF) luciferase activity.
- Chemical Name: 2-[4-(1-Methylethyl)phenyl]-4H-1-benzopyran-4-one
- Formula: C18H16O2
- CAS Number: 92831-11-3
- Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
- Purity: >98
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