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MOG Mouse anti-Human, Mouse, Rat, Clone: CL2852, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524644

Catalog No. PIMA524644


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Description

Description

Immunogen sequence: ALVGDEVELP CRISPGKNAT GMEVGWYRPP FSRVVHLYRN GKDQDGDQAP EYRGRTELLK DAIGEGKVTL RIRNVRFSDE GGFTCFFRDH SYQEEAAMEL KVEDPFYWVS PG Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 89%. Binds to an epitope located within the peptide sequence FSRVVHLYRNGKDQD as determined by overlapping synthetic peptides.

Myelin / Oligodendrocyte Specific Protein (MOSP) (pI of ~6.7) is found exclusively on oligodendrocytes and myelin in the central nervous system (CNS). Myelin is produced by oligodendrocytes in the CNS and Schwann cells in the peripheral nervous system (PNS). Defining the differences between CNS and PNS myelin may provide insights into the process of myelination and the pathogenesis of certain idiopathic diseases involving myelin such as multiple sclerosis, certain leukodystrophies, and other myelinopathies. On demyelination, immunoreactivity for MOSP, like MBP, is lost.
Specifications

Specifications

MOG
Monoclonal
1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q16653, Q61885, Q63345
MOG; MGC26137; myelin oligodendrocyte glycoprotein; DAQB-92E24.2; MOGIG-2; MOG Ig-AluB; MOG alpha-6
Mouse
IgG1
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
17441, 24558, 4340
Immunohistochemistry, Western Blot
CL2852
Unconjugated
MOG
Liquid
MOG
Recombit protein corresponding to Human MOG
Protein A
RUO
Antibody
Monoclonal
Human, Mouse, Rat
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