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Mouse anti-AMPD3, Clone: AMPD3/901, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2444410.02MG

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Catalog No. NBP24444100


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Description

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence

AMPD3 Monoclonal antibody specifically detects AMPD3 in Human samples. It is validated for Flow Cytometry, Immunohistochemistry-Paraffin, Immunofluorescence, Immunocytochemistry.
Specifications

Specifications

AMPD3
AMPD3/901
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Purified
AMPD3
Recombinant full-length human AMDP3 protein
Protein A or G purified
RUO
Primary
272
Human
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
0.2mg/mL
Flow Cytometry 1 - 2 ug/million cells in 0.1ml, Immunohistochemistry-Paraffin 2 - 4 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml, Immunocytochemistry 1 - 2.0 ug/ml
Q01432
adenosine monophosphate deaminase (isoform E), adenosine monophosphate deaminase 3, AMP aminohydrolase, AMP deaminase 3, AMP deaminase isoform E, EC 3.5.4.6, Erythrocyte AMP deaminase, erythrocyte type AMP deaminase, erythrocyte-specific AMP deaminase, myoadenylate deaminase
Mouse
IgG2b Kappa
0.02 mg
Store at 4C.
Monoclonal
It recognizes a protein of ~90kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.
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