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Mouse anti-Androgen R/NR3C4, Clone: AR441 + DHTR/882, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2447890.2MG

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Catalog No. NBP24478902

This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Ensure accurate, reproducible results in Immunohistochemistry (Paraffin), Immunofluorescence

Specifications

Specifications

Androgen R/NR3C4
AR441 + DHTR/882
Unconjugated
1.0mM PBS and 0.05% BSA with 0.05% Sodium Azide
Purified
AR
A synthetic peptide, aa 299-315, (STEDTAEYSPFKGGYTK) of human AR (AR441); Recombinant human DHTR protein (DHTR/882)
110 kDa
0.2 mg
Breast Cancer, Cancer, Cellular Markers
Primary
367
Human, Mouse (Negative)
Immunohistochemistry (Paraffin), Immunofluorescence
0.2mg/mL
Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
P10275
AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy
Mouse
IgG
Protein A or G purified
RUO
Store at 4C.
Monoclonal
Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.
Documents
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