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Mouse anti-Bax, Clone: BAX/962, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2444200.2MG

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Catalog No. NBP24442002

This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Ensure accurate, reproducible results in Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Specifications

Specifications

Bax
BAX/962
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Purified
Mouse
IgG1
Protein A or G purified
RUO
Store at 4C.
Monoclonal
Recognizes a protein of 21kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
0.2mg/mL
Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
Q07812
apoptosis regulator BAX, BCL2-associated X protein, Bcl2-L-4, BCL2L4bcl2-L-4, Bcl-2-like protein 4
Recombinant full-length human BAX protein.
21 kDa
0.2 mg
Apoptosis, Cancer, Core ESC Like Genes, Stem Cell Markers, Tumor Suppressors
Primary
581
Human, Monkey, Mouse (Negative), Rat (Negative)
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