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Mouse anti-Bcl-2, Clone: 100/D5, Novus Biologicals™

Mouse Monoclonal Antibody

$366.50 - $402.50

Specifications

Antigen Bcl-2
Clone 100/D5
Concentration 0.2mg/mL
Immunogen The synthetic peptide corresponding to amino acids range from 41-64 (GAAPAPGIFSSQPG-Cys), of human Bcl-2 was used as immunogen to generate the antibody; GenBank no. NP_000648.2 (Pezzella et al, 1990).
Gene Accession No. P10415
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
NBP21520001
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Novus Biologicals
NBP2152000.1MG
0.1 mg
Each for $366.50
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NBP21520002
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Novus Biologicals
NBP2152000.2MG
0.2 mg
Each for $402.50
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Description

Description

Bcl-2 Monoclonal antibody specifically detects Bcl-2 in Human, Mouse (Negative), Rat (Negative) samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
Specifications

Specifications

Bcl-2
0.2mg/mL
P10415
PBS with 0.05% BSA. with 0.05% Sodium Azide
This antibody recognizes a protein of 25-26kDa, identified as the bcl-2alpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2alpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2alpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative.
Primary
Mouse
Unconjugated
Protein G purified
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
100/D5
The synthetic peptide corresponding to amino acids range from 41-64 (GAAPAPGIFSSQPG-Cys), of human Bcl-2 was used as immunogen to generate the antibody; GenBank no. NP_000648.2 (Pezzella et al, 1990).
596
Outer mitochondrial membranes and endoplasmic reticulum as well as nuclear membranes.
Monoclonal
Store at 4C.
IgG1 Kappa
Purified
RUO
SDS
Product Certifications

For Research Use Only

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