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Mouse anti-Bcl-2, Clone: BCL2/796, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2447840.02MG

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Catalog No. NBP24478400


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Description

Description

Ensure accurate, reproducible results in Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Bcl-2 Monoclonal antibody specifically detects Bcl-2 in Human samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry-Paraffin, Immunofluorescence.
Specifications

Specifications

Bcl-2
BCL2/796
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Purified
BCL2
Recombinant full-length human bcl-2 protein
25.5 kDa
0.02 mg
Apoptosis, Autophagy, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Tumor Suppressors
Primary
596
Human
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
0.2mg/mL
Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
P10415
apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2
Mouse
IgG1 Kappa
Protein A or G purified
RUO
Store at 4C.
Monoclonal
This antibody recognizes a protein of 25-26kDa, identified as the bcl-2 alpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2 alpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative.
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