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Mouse anti-beta 2-Microglobulin, Clone: C21.48A1, Novus Biologicals™

Mouse Monoclonal Antibody

$129.00 - $299.00

Specifications

Antigen beta 2-Microglobulin
Clone C21.48A1
Concentration 0.2 mg/mL
Immunogen Soluble beta 2 microglobulin
Gene ID (Entrez) 567
View More Specs

Products 3
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
NBP24447000 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2444700.02MG
0.02 mg Each for $129.00
Add to cart
 
NBP24447001 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2444700.1MG
0.1 mg Each for $299.00
Add to cart
 
NBP24447002 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2444700.2MG
0.2 mg This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence

beta 2-Microglobulin Monoclonal antibody specifically detects beta 2-Microglobulin in Human, Primate samples. It is validated for Flow Cytometry, SDS-Page, Immunofluorescence.
Specifications

Specifications

beta 2-Microglobulin
0.2 mg/mL
567
Monoclonal
Mouse
IgG2b Kappa
Purified
RUO
Protein A or G purified
C21.48A1
Soluble beta 2 microglobulin
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Primary
The antibody recognizes the hidden determinant of beta-2 microglobulin (i.e. binding to its determinant is available only when the chain is separated from the HLA heavy chain. beta-2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. beta2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy).
Unconjugated
Flow Cytometry, SDS-Page, Immunofluorescence
Store at 4C.

For Research Use Only

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