Mouse anti-CCL16/HCC-4/LEC, Clone: LEC66, Azide Free, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2346660.2 MG

Catalog No. NBP23466602

Description

CCL16/HCC-4/LEC Monoclonal antibody specifically detects CCL16/HCC-4/LEC in Human samples. It is validated for ELISA, Functional.

Specifications

• Antigen: CCL16/HCC-4/LEC
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Dilution: ELISA 1-5ug/ml for coating, Functional
• Gene Accession No.: O15467
• Gene Symbols: CCL16
• Immunogen: Recombinant human HCC-4 protein
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Gene ID (Entrez): 6360
• Reconstitution: Protein A purified
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Isotype: IgG1 κ

• Applications: ELISA, Functional Assay
• Clone: LEC66
• Conjugate: Unconjugated
• Formulation: 10mM PBS - BSA free with No Preservative
• Gene Alias: C-C motif chemokine 16, chemokine (C-C motif) ligand 16, Chemokine CC-4, Chemokine LEC, CKb12, HCC-4Liver-expressed chemokine, LCC-1Lymphocyte and monocyte chemoattractant, LEC, liver CC chemokine-1, LMCSmall-inducible cytokine A16, monotactin-1, MTN-1, NCC4IL-10-inducible chemokine, NCC-4ILINCK, new CC chemokine 4, SCYA16MGC117051, SCYL4, small inducible cytokine subfamily A (Cys-Cys), member 16
• Host Species: Mouse
• Molecular Weight of Antigen: 11 kDa
• Quantity: 0.2 mg
• Primary or Secondary: Primary
• Test Specificity: Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelo-suppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones. The ability of HCC-4 to markedly improve recognition of poorly immunogenic cells suggests that it could be an effective component of antitumor vaccines.
• Target Species: Human
• Form: Purified

For Research Use Only