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Mouse anti-CD11c, Clone: ITGAX/1242, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2445980.02MG

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Catalog No. NBP24459800


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Description

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

CD11c Monoclonal antibody specifically detects CD11c in Human samples. It is validated for Flow Cytometry, Immunohistochemistry-Paraffin, SDS-Page, Immunofluorescence.
Specifications

Specifications

CD11c
ITGAX/1242
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
95, 95 alpha chain, 95, alpha subunit, CD11 antigen-like family member C, CD11c, CD11c antigen, CD11Cleu M5, alpha subunit, integrin alpha-X, integrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit), Leu M5, Leukocyte adhesion glycoprotein p150, Leukocyte adhesion receptor p150, leukocyte surface antigen p150, myeloid membrane antigen, alpha subunit, p150 95 integrin alpha chain, SLEB6
Mouse
IgG Kappa
Protein A or G purified
RUO
Store at 4C.
Monoclonal
Recognizes a protein of 145kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues.
Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
0.2 mg/mL
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Purified
CD11c
Recombinant fragment (191 Amino acid residues between aa 600-850) of human ITGAX protein
145 kDa
0.02 mg
Dendritic Cell Markers, Signal Transduction
Primary
3687
Human
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