Mouse anti-CD30/TNFRSF8, Clone: Ber-H2, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP2445591ML
Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), ImmunofluorescenceCD30/TNFRSF8 Monoclonal antibody specifically detects CD30/TNFRSF8 in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence.
|No buffer with 0.05% Sodium Azide|
|Co cell line established from a patient with Hodgkin s disease of T-cell lineage|
|Tissue culture supernatant|
|Store at 4C.|
|Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. Its epitope is located between aa112-412. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).|
|Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence|
|Flow Cytometry 5 - 10 ul/million cells in 0.1ml, Immunohistochemistry, Immunohistochemistry-Paraffin 1:50 - 1:100, Immunofluorescence 1:50 - 1:100|
|CD30, CD30 antigen, CD30KI-1, CD30L receptor, cytokine receptor CD30, D1S166EKi-1, Ki-1 antigen, Lymphocyte activation antigen CD30, tumor necrosis factor receptor superfamily member 8, tumor necrosis factor receptor superfamily, member 8|
|Apoptosis, Cell Cycle and Replication, Embryonic Stem Cell Markers, Immunology, Stem Cell Markers|
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