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Mouse anti-CD34, Clone: HPCA1/1171, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2445690.1MG

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Catalog No. NBP24456901


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Description

Description

Ensure accurate, reproducible results in Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

CD34 Monoclonal antibody specifically detects CD34 in Human, Rat samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry-Paraffin, SDS-Page, Immunofluorescence.
Specifications

Specifications

CD34
HPCA1/1171
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Purified
CD34
Recombinant full-length human HPCA1 protein
Protein A or G purified
RUO
Store at 4C.
Monoclonal
This antibody recognizes a carbohydrate epitope on a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34 (VI international workshop on human differentiation antigens). Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi s sarcoma, but shows low specificity.
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
0.2mg/mL
Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 2 - 4 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
P28906
CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule
Mouse
IgG1 Kappa
0.1 mg
Adaptive Immunity, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors
Primary
947
Human, Rat
Documents
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