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CD344 Mouse anti-Human, Alexa Fluor 647, Clone: CH3A4A7, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 564886

Catalog No. BDB564886


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Description

Description

The CH3A4A7 monoclonal antibody reacts with an extracellular epitope on human CD344 which is also known as Frizzled family receptor 4 (FZD4) or Frizzled-4. CD344 is a member of the Frizzled family of proteins within the G protein-coupled receptor (GPCR) superfamily. CD344 is a receptor for Wnt proteins and participates in the activation of the Wnt/beta-catenin pathway (canonical Wnt signaling). Patients with familial exudative vitreoretinopathy (FEVR) carry mutations in Frizzled-4. This disease is characterized by retinal degeneration and hearing loss. On tissues, CD344 is almost ubiquitously expressed. CD344 is highly expressed in adult heart and skeletal muscle.

Specifications

Specifications

CD344
CH3A4A7
FZD4; Frizzled family receptor 4; Frizzled-4; Fz-4; FzE4; hFz4; EVR1; FEVR
Affinity Purified
Human neuroblastoma Cell Line
Affinity Chromatography
RUO
Primary
Human
Flow Cytometry
Alexa Fluor 647
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Murine
IgG1, κ
100 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Documents
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