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Mouse anti-CD46, Clone: 122.2, Novus Biologicals™

Mouse Monoclonal Antibody

Specifications

Antigen CD46
Clone 122.2
Concentration 0.2mg/mL
Immunogen A recombinant protein fragment specific for human CD46 was used as the immunogen.
Gene Accession No. NP_002380
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
NBP22522202
View Documents
Novus Biologicals
NBP2252220.02MG
0.02 mg
Each for $156.50
N/A
NBP2252222M
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Novus Biologicals
NBP2252220.2MG
0.2 mg This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
Description

Description

CD46 Monoclonal antibody specifically detects CD46 in Human samples. It is validated for Flow Cytometry, SDS-Page, Immunofluorescence.
Specifications

Specifications

CD46
0.2mg/mL
NP_002380
PBS with 0.05% BSA. with 0.05% Sodium Azide
Monoclonal
Store at 4C.
IgG1 Kappa
Purified
RUO
122.2
A recombinant protein fragment specific for human CD46 was used as the immunogen.
4179
CD46 acts as a cofactor for complement factor I, a serine protease, which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. It may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 acts as a co-stimulatory factor for T-cells, which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.
Primary
Mouse
Unconjugated
Protein G purified
Flow Cytometry, SDS-Page, Immunofluorescence
SDS
Product Certifications

For Research Use Only

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