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CD63 Antibody (LAMP3/968), Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP2448100.2MG
Description
Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
CD63 Monoclonal antibody specifically detects CD63 in Human samples. It is validated for Flow Cytometry, Immunohistochemistry-Paraffin, SDS-Page, Immunofluorescence.Specifications
CD63 | |
Monoclonal | |
0.2mg/mL | |
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml | |
P08962 | |
CD63 | |
Recombinant human full-length CD63 protein | |
0.2 mg | |
Autophagy, Cancer, Cardiovascular Biology, Cellular Signaling, Cytokine Research, Immunology, Innate Immunity, Lysosome Markers | |
967 | |
Human | |
Purified |
Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence | |
LAMP3/968 | |
Unconjugated | |
10mM PBS and 0.05% BSA with 0.05% Sodium Azide | |
CD63 antigen, CD63 antigen (melanoma 1 antigen), CD63 molecule, Granulophysin, LAMP-3, Lysosomal-associated membrane protein 3, ME491, melanoma 1 antigen, Melanoma-associated antigen ME491, melanoma-associated antigen MLA1, MLA1lysosome-associated membrane glycoprotein 3, Ocular melanoma-associated antigen, OMA81H, Tetraspanin-30, tspan-30, TSPAN30granulophysin | |
Mouse | |
Protein A or G purified | |
RUO | |
Primary | |
This MAb recognizes protein of 26kDa-60kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly express | |
Store at 4C. | |
IgG2a κ |
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