Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Mouse anti-Complement 4d, Clone: C4D205, Novus Biologicals™

Mouse Monoclonal Antibody

$129.00 - $299.00

Specifications

Antigen Complement 4d
Clone C4D205
Concentration 0.2 mg/mL
Immunogen Recombinant human Complement 4d protein
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
View More Specs

Products 3
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
NBP24479001 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2447900.1MG
0.1 mg Each for $299.00
Add to cart
 
NBP24479000 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2447900.02MG
0.02 mg Each for $129.00
Add to cart
 
NBP24479002 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2447900.2MG
0.2 mg This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Ensure accurate, reproducible results in ELISA, Immunofluorescence

Complement C4b/d Monoclonal antibody specifically detects Complement C4b/d in Human samples. It is validated for SDS-Page, Immunofluorescence.
Specifications

Specifications

Complement 4d
0.2 mg/mL
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Primary
This MAb is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound C4d. C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of Abs to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product Complement 4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. It has been shown to be a significant predictor of transplant kidney graft survival. Anti-C4d, combined with anti-C3d, can be utilized as a tool for diagnosis of allograft rejection that may warrant a prompt and aggressive anti-rejection treatment.
Unconjugated
SDS-Page, Immunofluorescence
Store at 4C.
C4D205
Recombinant human Complement 4d protein
Monoclonal
Mouse
IgG1
Purified
RUO
Protein A or G purified

For Research Use Only

Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit