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Mouse anti-Complement 4d, Clone: TDM16, Novus Biologicals™

Mouse Monoclonal Antibody

$129.00 - $299.00

Specifications

Antigen Complement 4d
Clone TDM16
Concentration 0.2 mg/mL
Immunogen Human Complement 4d protein
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
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Products 3
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
NBP24479300 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2447930.02MG
0.02 mg Each for $129.00
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NBP24479301 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2447930.1MG
0.1 mg Each for $299.00
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NBP24479302 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2447930.2MG
0.2 mg This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Ensure accurate, reproducible results in ELISA, Immunofluorescence

Complement C4b/d Monoclonal antibody specifically detects Complement C4b/d in Human samples. It is validated for Immunofluorescence.
Specifications

Specifications

Complement 4d
0.2 mg/mL
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Primary
This MAb is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound C4d.C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of Abs to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product Complement 4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. It has been shown to be a significant predictor of transplant kidney graft survival. Anti-C4d, combined with anti-C3d, can be utilized as a tool for diagnosis of allograft rejection that may warrant a prompt and aggressive anti-rejection treatment.
Unconjugated
Immunofluorescence
Store at 4C.
TDM16
Human Complement 4d protein
Monoclonal
Mouse
IgG1
Purified
RUO
Protein A or G purified

For Research Use Only

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