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Mouse anti-Cyclin D1, Clone: DCS-6, Azide Free, Novus Biologicals™

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2331380.2MG

Catalog No. NBP23313802

This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Specifications

Specifications

Cyclin D1
DCS-6
Unconjugated
10mM PBS - BSA free with No Preservative
B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, BCL1D11S287E, cyclin D1, cyclin D1 (PRAD1: parathyroid adenomatosis 1), G1/S-specific cyclin D1, G1/S-specific cyclin-D1, PRAD1 oncogene, PRAD1B-cell CLL/lymphoma 1, U21B31
Mouse
IgG2a Kappa
0.2 mg
Cancer, Cell Cycle and Replication, Core ESC Like Genes, mTOR Pathway, Stem Cell Markers, Wnt Signaling Pathway
Primary
595
Human, Mouse, Rat, Primate
ELISA
1.0 mg/mL
ELISA 1-5ug/ml for coating
Purified
CCND1
Human recombinant full length Cyclin D1 protein was used as immunogen to generate this antibody.
Protein G purified
RUO
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Monoclonal
Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
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