Mouse anti-Cytochrome b245 alpha, Clone: CS9, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP1409740.1MG
DescriptionCytochrome b245 alpha Monoclonal antibody specifically detects Cytochrome b245 alpha in Human samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Frozen.
|Cytochrome b245 alpha|
|PBS (pH 7.4) with 0.09% Sodium Azide|
|Cytochrome B245 solubilised in octyl-beta-gluycopyranoside|
|Protein G purified|
|ELISA, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot|
|Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:100, ELISA 1:100-1:2000, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500|
|cytochrome b light chain, Cytochrome b(558) alpha chain, cytochrome b(558) alpha-subunit, cytochrome b, alpha polypeptide, cytochrome b-245 light chain, cytochrome b-245, alpha polypeptide, Cytochrome b558 subunit alpha, flavocytochrome b-558 alpha polypeptide, Neutrophil cytochrome b 22 kDa polypeptide, p22 phagocyte B-cytochrome, p22phox, p22-phox, Superoxide-generating NADPH oxidase light chain subunit|
|Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.|
|This antibody recognises the light chain of cytochrome B245, also known as p22phox, a subunit of the nicotinamide adenine dinucleotide phosphate-oxidase (NADPH oxidase). NADPH oxidase is a membrane-bound enzyme complex in neutrophils that produces the superoxide anion (O2-) by transferring single electrons from NADPH inside the cell across the membrane and coupling them to molecular oxygen. Superoxide is used for the destruction of pathogens. Individuals with defects in NADPH oxidase suffer from chronic granulomatous disease, characterised by severe recurrent infections.|
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